Studies on new dehydropeptidase inhibitors. III. Biological properties of WS1358A1.
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چکیده
منابع مشابه
Studies on new dehydropeptidase inhibitors. III. Biological properties of WS1358A1.
WS1358A1, a novel inhibitor of renal dehydropeptidase (DHP), augmented the urinary recovery of a carbapenem antibiotic imipenem and improved its protective effect in experimental infections when simultaneously administered to mice with the antibiotic. WS1358A1 was a competitive DHP inhibitor with a Ki value of 1.6 x 10(-7) M.
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1990
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.43.281